Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
KGQ21866.1Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (575 aa)    
Predicted Functional Partners:
KGQ21865.1
Sodium:solute symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.925
KGQ21867.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.921
KGQ21869.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.892
KGQ21113.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.855
KGQ21634.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.823
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.813
KGQ21868.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.788
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.706
KGQ22803.1
2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.696
KGQ21321.2
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.542
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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