Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rexREX family transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (211 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. Belongs to the RnpA family.
   
    0.869
KGQ22813.1
Tetratricopeptide repeat protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.810
KGQ21525.2
Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.799
KGQ22822.2
HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.558
rpsP
30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.511
KGQ22776.2
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.496
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.471
murE
UDP-N-acetylmuramyl peptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
     
 0.460
KGQ21667.2
EDD domain protein, DegV family; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.422
KGQ21702.2
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.416
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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