Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KGQ22875.1Peptigoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)    
Predicted Functional Partners:
KGQ22186.2
Cell division protein FtsX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 
 0.901
KGQ21990.1
Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family.
  
 
 0.828
KGQ21247.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.816
KGQ21974.2
Cell division protein FtsE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.808
KGQ21104.2
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.786
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.757
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.677
KIX84571.1
Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.649
KIX84369.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.643
KGQ22077.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.625
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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