Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irak3Interleukin 1 receptor associated kinase 3. (657 aa)    
Predicted Functional Partners:
traf6
TNF receptor associated factor 6.
   
 0.992
irak1
Interleukin 1 receptor associated kinase 1.
    
 0.992
irak4
Interleukin 1 receptor associated kinase 4.
    
 0.985
ngfr
Nerve growth factor receptor.
    
  0.885
LOC114663558
Tumor necrosis factor receptor superfamily member 16-like.
    
  0.880
traf7
TNF receptor associated factor 7.
   
 0.860
myd88
MYD88 innate immune signal transduction adaptor.
    
 0.829
tirap
TIR domain containing adaptor protein.
   
 0.752
casp6
Caspase 6.
    
 0.742
ENSECRP00000011256
annotation not available
   
 0.740
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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