Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
klKlotho. (976 aa)    
Predicted Functional Partners:
fgf23
Fibroblast growth factor 23.
    
 0.898
gusb
Glucuronidase beta.
    
 0.876
galm
Galactose mutarotase.
  
 
 0.874
LOC114650026
Fibroblast growth factor receptor 1-like.
    
 0.863
glb1
Galactosidase beta 1.
  
 
 0.852
gla
Galactosidase alpha.
     
 0.846
rgn
Regucalcin.
    
  0.846
LOC114658163
Glucuronokinase 1-like.
    
 0.837
LOC114656165
UDP-glucuronosyltransferase 1-1-like.
     
 0.836
gck
Glucokinase.
     
 0.834
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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