STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tp73Tumor protein p73. (583 aa)    
Predicted Functional Partners:
mdm2
MDM2 proto-oncogene.
    
 0.953
atm
ATM serine/threonine kinase.
   
 0.938
tp53
Tumor protein p53.
  
 
0.932
chek2
Checkpoint kinase 2.
    
 0.931
LOC114643508
Serine/threonine-protein kinase ATR-like.
    
 0.925
chek1
Checkpoint kinase 1.
    
 0.906
sirt1
Sirtuin 1.
    
 0.902
mdm4
MDM4 regulator of p53.
    
 0.896
wrn
WRN RecQ like helicase.
    
 0.894
LOC114660460
PWWP domain-containing protein 2A-like.
   
 0.880
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.