STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh3pxd2aSH3 and PX domains 2A. (1095 aa)    
Predicted Functional Partners:
pak4
P21 (RAC1) activated kinase 4.
    
 0.760
pak1
P21 (RAC1) activated kinase 1.
    
 0.760
pak5
P21 (RAC1) activated kinase 5.
    
 0.760
pak6
P21 (RAC1) activated kinase 6.
    
 0.760
pak3
P21 (RAC1) activated kinase 3.
    
 0.760
pak2
P21 (RAC1) activated kinase 2.
    
 0.760
tiam2
TIAM Rac1 associated GEF 2.
    
 0.748
arhgef4
Rho guanine nucleotide exchange factor 4.
    
 0.748
prex2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
    
 0.748
prex1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
    
 0.748
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.