STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crkCRK proto-oncogene, adaptor protein. (309 aa)    
Predicted Functional Partners:
rapgef1
Rap guanine nucleotide exchange factor 1.
    
 0.981
abl2
ABL proto-oncogene 2, non-receptor tyrosine kinase.
    
0.956
abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
    
0.956
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.954
gab1
GRB2 associated binding protein 1.
    
 0.945
pxn
Paxillin.
    
 0.941
ptk2
Protein tyrosine kinase 2.
    
 0.924
egfr
Epidermal growth factor receptor.
    
 0.916
dock5
Dedicator of cytokinesis 5.
    
 0.915
dock2
Dedicator of cytokinesis 2.
    
 0.915
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.