STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cflarCASP8 and FADD like apoptosis regulator. (475 aa)    
Predicted Functional Partners:
fadd
Fas associated via death domain.
    
 0.994
ripk1
Receptor interacting serine/threonine kinase 1.
    
 0.990
fas
Fas cell surface death receptor.
   
 0.989
casp8
Caspase 8.
   
0.979
LOC114655292
Caspase-8-like.
 
 
0.976
LOC114655293
Caspase-8-like.
   
0.976
itch
Itchy E3 ubiquitin protein ligase.
    
 0.973
LOC114655228
Uncharacterized LOC114655228.
   
 0.955
atg3
Autophagy related 3.
    
 0.938
apaf1
Apoptotic peptidase activating factor 1.
    
 0.919
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.