STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plekhg6Pleckstrin homology and RhoGEF domain containing G6. (980 aa)    
Predicted Functional Partners:
ripk1
Receptor interacting serine/threonine kinase 1.
   
 0.922
tradd
TNFRSF1A associated via death domain.
    
 0.918
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.875
fadd
Fas associated via death domain.
   
 0.870
chuk
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.831
tnfaip3
TNF alpha induced protein 3.
    
 0.828
traf6
TNF receptor associated factor 6.
    
 0.809
bag4
BCL2 associated athanogene 4.
    
 0.802
nsmaf
Neutral sphingomyelinase activation associated factor.
    
 0.793
fas
Fas cell surface death receptor.
    
 0.790
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.