STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh2b1SH2B adaptor protein 1. (723 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor bound protein 2.
    
 0.910
insrr
Insulin receptor related receptor.
    
 0.871
insr
Insulin receptor.
    
 0.871
igf1r
Insulin like growth factor 1 receptor.
    
 0.871
sh2b3
SH2B adaptor protein 3.
    
 
0.843
cblb
Cbl proto-oncogene B.
    
 0.810
cbl
Cbl proto-oncogene.
    
 0.810
LOC114667364
E3 ubiquitin-protein ligase CBL-C-like.
    
 0.810
jak1
Janus kinase 1.
    
 0.770
jak2
Janus kinase 2.
    
 0.770
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.