STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erbb2Erb-b2 receptor tyrosine kinase 2. (1266 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor bound protein 2.
    
 0.978
egf
Epidermal growth factor.
   
 0.973
tgfa
Transforming growth factor alpha.
    
 0.951
met
MET proto-oncogene, receptor tyrosine kinase.
   
0.951
ENSECRP00000022943
annotation not available
    
0.950
shc1
SHC adaptor protein 1.
    
 0.949
ereg
Epiregulin.
    
 0.949
shc3
SHC adaptor protein 3.
    
 0.949
ctnnb1
Catenin beta 1.
    
 0.945
shc2
SHC adaptor protein 2.
    
 0.940
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.