STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgcr3-hydroxy-3-methylglutaryl-CoA reductase. (883 aa)    
Predicted Functional Partners:
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
  
 
 0.998
mvk
Mevalonate kinase.
  
 0.961
mvd
Mevalonate diphosphate decarboxylase.
  
 
 0.953
ubiad1
UbiA prenyltransferase domain containing 1.
   
 
 0.946
sqle
Squalene epoxidase.
  
  
 0.939
LOC114642276
Lanosterol 14-alpha demethylase.
  
  
 0.935
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
    
 0.899
insig1
Insulin induced gene 1.
   
 
 0.890
insig2
Insulin induced gene 2.
   
 
 0.890
LOC114643391
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic-like.
    
 0.888
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.