STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rab5aRAB5A, member RAS oncogene family. (216 aa)    
Predicted Functional Partners:
rabgef1
RAB guanine nucleotide exchange factor 1.
   
 0.973
LOC114668527
Rab5 GDP/GTP exchange factor-like.
   
 0.972
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.956
eea1
Early endosome antigen 1.
    
 0.953
rbsn
Rabenosyn, RAB effector.
   
 0.936
appl2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.917
appl1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.917
gapvd1
GTPase activating protein and VPS9 domains 1.
    
 0.871
gdi2
GDP dissociation inhibitor 2.
   
 0.865
LOC114660500
Rab GDP dissociation inhibitor alpha-like.
   
 0.865
Your Current Organism:
Erpetoichthys calabaricus
NCBI taxonomy Id: 27687
Other names: Calamoichthys calabaricus, E. calabaricus, reedfish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.