STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
R7Q5X1_CHOCRBifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (515 aa)    
Predicted Functional Partners:
R7Q8U9_CHOCR
dUTPase domain-containing protein.
  
 0.996
R7Q5I2_CHOCR
Thymidylate_kin domain-containing protein.
  
 
 0.993
R7QF28_CHOCR
CMP/dCMP-type deaminase domain-containing protein.
  
 
 0.993
R7Q8V1_CHOCR
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.990
R7QGY1_CHOCR
Serine hydroxymethyltransferase, cytosolic (Glycine hydroxymethyltransferase).
  
 
 0.990
S0F2S0_CHOCR
Serine hydroxymethyltransferase, cytosolic (Glycine hydroxymethyltransferase).
  
 
 0.990
R7QG86_CHOCR
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.989
R7QEH6_CHOCR
Formate--tetrahydrofolate ligase.
  
 
 0.986
R7QC97_CHOCR
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.979
R7QKH3_CHOCR
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.979
Your Current Organism:
Chondrus crispus
NCBI taxonomy Id: 2769
Other names: C. crispus, Irish moss, carageen, carrageen, carragheen
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.