STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R7Q8D5_CHOCRDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (720 aa)    
Predicted Functional Partners:
R7QN73_CHOCR
Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.782
R7Q7T1_CHOCR
Uncharacterized protein.
    
 
 0.735
R7QV80_CHOCR
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
    
 0.658
R7QIH4_CHOCR
Rad60-SLD domain-containing protein.
    
 0.635
R7QUS6_CHOCR
Uncharacterized protein.
    
 0.635
R7QSQ0_CHOCR
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
    
 
 0.606
R7QE00_CHOCR
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 
 0.589
R7Q7F6_CHOCR
Uncharacterized protein.
   
 
 0.564
R7Q723_CHOCR
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner.
   
 
 0.557
R7QHX8_CHOCR
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.557
Your Current Organism:
Chondrus crispus
NCBI taxonomy Id: 2769
Other names: C. crispus, Irish moss, carageen, carrageen, carragheen
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