STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R7QJC4_CHOCRDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (638 aa)    
Predicted Functional Partners:
R7Q7F6_CHOCR
Uncharacterized protein.
   
 0.860
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.803
R7QDZ0_CHOCR
Ku core domain, Ku70 family.
  
 
 0.746
R7QKI6_CHOCR
DNA ligase.
  
 0.742
R7QQL7_CHOCR
Putative ATP dependent DNA ligase.
  
 0.742
R7QBC3_CHOCR
Uncharacterized protein.
    
 0.710
R7QLS7_CHOCR
Uncharacterized protein.
    
 0.706
R7Q5C6_CHOCR
Uncharacterized protein.
  
 0.689
R7Q9S7_CHOCR
Uncharacterized protein.
   
 0.644
R7QQV6_CHOCR
Ku domain-containing protein.
     
 0.600
Your Current Organism:
Chondrus crispus
NCBI taxonomy Id: 2769
Other names: C. crispus, Irish moss, carageen, carrageen, carragheen
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