node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | R7Q5D0_CHOCR | R7Q7A4 | R7Q5D0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | R7Q7I3_CHOCR | R7Q7A4 | R7Q7I3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.994 |
MCM7 | R7QBI0_CHOCR | R7Q7A4 | R7QBI0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | ORC_WH_C domain-containing protein. | 0.979 |
MCM7 | R7QC59_CHOCR | R7Q7A4 | R7QC59 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein 6, CDC6. | 0.998 |
MCM7 | R7QNM9_CHOCR | R7Q7A4 | R7QNM9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 5, ORC5. | 0.980 |
MCM7 | R7QNS9_CHOCR | R7Q7A4 | R7QNS9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | CDT1 domain-containing protein. | 0.999 |
MCM7 | R7QS36_CHOCR | R7Q7A4 | R7QS36 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 2, ORC2. | 0.994 |
MCM7 | R7QSM4_CHOCR | R7Q7A4 | R7QSM4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.995 |
MCM7 | R7QT75_CHOCR | R7Q7A4 | R7QT75 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | R7QUI7_CHOCR | R7Q7A4 | R7QUI7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
R7Q5D0_CHOCR | MCM7 | R7Q5D0 | R7Q7A4 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
R7Q5D0_CHOCR | R7Q7I3_CHOCR | R7Q5D0 | R7Q7I3 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.995 |
R7Q5D0_CHOCR | R7QBI0_CHOCR | R7Q5D0 | R7QBI0 | DNA helicase; Belongs to the MCM family. | ORC_WH_C domain-containing protein. | 0.918 |
R7Q5D0_CHOCR | R7QC59_CHOCR | R7Q5D0 | R7QC59 | DNA helicase; Belongs to the MCM family. | Cell division control protein 6, CDC6. | 0.998 |
R7Q5D0_CHOCR | R7QNM9_CHOCR | R7Q5D0 | R7QNM9 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 5, ORC5. | 0.990 |
R7Q5D0_CHOCR | R7QNS9_CHOCR | R7Q5D0 | R7QNS9 | DNA helicase; Belongs to the MCM family. | CDT1 domain-containing protein. | 0.999 |
R7Q5D0_CHOCR | R7QS36_CHOCR | R7Q5D0 | R7QS36 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 2, ORC2. | 0.997 |
R7Q5D0_CHOCR | R7QSM4_CHOCR | R7Q5D0 | R7QSM4 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.996 |
R7Q5D0_CHOCR | R7QT75_CHOCR | R7Q5D0 | R7QT75 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
R7Q5D0_CHOCR | R7QUI7_CHOCR | R7Q5D0 | R7QUI7 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |