node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R7Q1Q5_CHOCR | R7Q3T8_CHOCR | R7Q1Q5 | R7Q3T8 | NDK domain-containing protein; Belongs to the NDK family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.967 |
R7Q1Q5_CHOCR | R7Q4A1_CHOCR | R7Q1Q5 | R7Q4A1 | NDK domain-containing protein; Belongs to the NDK family. | Pyruvate kinase. | 0.905 |
R7Q1Q5_CHOCR | R7Q501_CHOCR | R7Q1Q5 | R7Q501 | NDK domain-containing protein; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase beta chain. | 0.944 |
R7Q1Q5_CHOCR | R7QBR9_CHOCR | R7Q1Q5 | R7QBR9 | NDK domain-containing protein; Belongs to the NDK family. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.905 |
R7Q1Q5_CHOCR | R7QFZ7_CHOCR | R7Q1Q5 | R7QFZ7 | NDK domain-containing protein; Belongs to the NDK family. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.904 |
R7Q1Q5_CHOCR | R7QKH3_CHOCR | R7Q1Q5 | R7QKH3 | NDK domain-containing protein; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.966 |
R7Q1Q5_CHOCR | R7QUB0_CHOCR | R7Q1Q5 | R7QUB0 | NDK domain-containing protein; Belongs to the NDK family. | Guanylate kinase-like domain-containing protein. | 0.958 |
R7Q3T8_CHOCR | R7Q1Q5_CHOCR | R7Q3T8 | R7Q1Q5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | NDK domain-containing protein; Belongs to the NDK family. | 0.967 |
R7Q3T8_CHOCR | R7Q4A1_CHOCR | R7Q3T8 | R7Q4A1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Pyruvate kinase. | 0.918 |
R7Q3T8_CHOCR | R7QBR9_CHOCR | R7Q3T8 | R7QBR9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.967 |
R7Q3T8_CHOCR | R7QEZ5_CHOCR | R7Q3T8 | R7QEZ5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.922 |
R7Q3T8_CHOCR | R7QFZ7_CHOCR | R7Q3T8 | R7QFZ7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.967 |
R7Q3T8_CHOCR | R7QG35_CHOCR | R7Q3T8 | R7QG35 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase (Glutamine-hydrolysing). | 0.954 |
R7Q3T8_CHOCR | R7QKH3_CHOCR | R7Q3T8 | R7QKH3 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.683 |
R7Q3T8_CHOCR | R7QUB0_CHOCR | R7Q3T8 | R7QUB0 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Guanylate kinase-like domain-containing protein. | 0.944 |
R7Q4A1_CHOCR | R7Q1Q5_CHOCR | R7Q4A1 | R7Q1Q5 | Pyruvate kinase. | NDK domain-containing protein; Belongs to the NDK family. | 0.905 |
R7Q4A1_CHOCR | R7Q3T8_CHOCR | R7Q4A1 | R7Q3T8 | Pyruvate kinase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.918 |
R7Q4A1_CHOCR | R7Q501_CHOCR | R7Q4A1 | R7Q501 | Pyruvate kinase. | Ribonucleoside-diphosphate reductase beta chain. | 0.900 |
R7Q4A1_CHOCR | R7QBR9_CHOCR | R7Q4A1 | R7QBR9 | Pyruvate kinase. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.905 |
R7Q4A1_CHOCR | R7QFZ7_CHOCR | R7Q4A1 | R7QFZ7 | Pyruvate kinase. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.905 |