STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS953Soluble guanylate cyclase gcy-35 (inferred by orthology to a C. elegans protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (359 aa)    
Predicted Functional Partners:
NBR_LOCUS18695
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.829
NBR_LOCUS12130
Uncharacterized protein.
    
 0.828
NBR_LOCUS3552
Nucleoside diphosphate kinase.
    
 0.821
NBR_LOCUS14599
Nucleoside diphosphate kinase (inferred by orthology to a C. elegans protein).
    
 0.821
NBR_LOCUS8589
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.817
NBR_LOCUS11888
cGMP-dependent protein kinase egl-4 (inferred by orthology to a C. elegans protein).
   
 0.786
NBR_LOCUS2622
Guanylate cyclase (inferred by orthology to a D. melanogaster protein).
 
 
 
  0.782
NBR_LOCUS246
Phosphodiesterase.
   
 0.763
NBR_LOCUS906
Obscurin-like protein 1 (inferred by orthology to a human protein).
     
 0.758
NBR_LOCUS955
Uncharacterized protein.
     
 0.758
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.