STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS1347Methylenetetrahydrofolate reductase. (233 aa)    
Predicted Functional Partners:
NBR_LOCUS9408
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.972
NBR_LOCUS10956
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.971
NBR_LOCUS9729
Cystathionine gamma-lyase (inferred by orthology to a human protein).
  
 0.958
NBR_LOCUS6740
Uncharacterized protein.
  
 0.957
NBR_LOCUS7371
Hcy-binding domain-containing protein.
  
 
 0.956
NBR_LOCUS5508
Methylenetetrahydrofolate reductase.
 
     0.946
NBR_LOCUS20348
Methylenetetrahydrofolate reductase.
 
     0.929
NBR_LOCUS576
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.924
NBR_LOCUS14001
Uncharacterized protein.
  
 
 0.922
NBR_LOCUS3479
Serine hydroxymethyltransferase (inferred by orthology to a C. elegans protein).
  
 
 0.915
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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