STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS1751Luc7-like protein 3 (inferred by orthology to a human protein). (355 aa)    
Predicted Functional Partners:
NBR_LOCUS2127
RRM domain-containing protein.
   
 0.980
NBR_LOCUS21879
RNA-binding protein 25 (inferred by orthology to a human protein).
   
 0.980
NBR_LOCUS10315
U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.
    
 0.976
NBR_LOCUS3837
U1 small nuclear ribonucleoprotein 70 kDa (inferred by orthology to a human protein).
   
 
 0.959
NBR_LOCUS19776
U1 small nuclear ribonucleoprotein 70 kDa (inferred by orthology to a human protein).
   
 
 0.959
NBR_LOCUS9673
Splicing factor 3B subunit 1 (inferred by orthology to a human protein).
   
 0.957
NBR_LOCUS9245
Uncharacterized protein.
   
  
 0.953
NBR_LOCUS11283
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.
    
 
 0.948
NBR_LOCUS10687
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
    
 0.946
NBR_LOCUS11420
AT20168p (inferred by orthology to a D. melanogaster protein).
   
  0.944
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.