STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS2439FANCI_HD2 domain-containing protein. (443 aa)    
Predicted Functional Partners:
NBR_LOCUS17097
Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein).
    
  0.939
NBR_LOCUS17443
Uncharacterized protein.
    
 0.933
NBR_LOCUS10052
Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein).
    
 0.825
NBR_LOCUS10991
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.825
NBR_LOCUS338
Ubiquitin-60S ribosomal protein L40 (inferred by orthology to a C. elegans protein).
    
  0.824
NBR_LOCUS18797
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
  0.823
NBR_LOCUS21452
Ubiquitin-conjugating enzyme E2 2 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.
   
 0.810
NBR_LOCUS8811
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.782
NBR_LOCUS17444
Uncharacterized protein.
    
 0.726
NBR_LOCUS22490
Uncharacterized protein.
    
 0.726
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.