node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NBR_LOCUS10956 | NBR_LOCUS11147 | A0A0N4Y4U9 | A0A0N4Y598 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Malate synthase; Belongs to the malate synthase family. | 0.408 |
NBR_LOCUS10956 | NBR_LOCUS15378 | A0A0N4Y4U9 | A0A0N4YF60 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate--cysteine ligase (inferred by orthology to a C. elegans protein). | 0.420 |
NBR_LOCUS10956 | NBR_LOCUS16536 | A0A0N4Y4U9 | A0A0N4YI20 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.825 |
NBR_LOCUS10956 | NBR_LOCUS20942 | A0A0N4Y4U9 | A0A0N4YUM0 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ADH_zinc_N domain-containing protein. | 0.463 |
NBR_LOCUS10956 | NBR_LOCUS22331 | A0A0N4Y4U9 | A0A0N4YYK8 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.825 |
NBR_LOCUS10956 | NBR_LOCUS4445 | A0A0N4Y4U9 | A0A0N4XPJ0 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aldo_ket_red domain-containing protein. | 0.771 |
NBR_LOCUS10956 | NBR_LOCUS5385 | A0A0N4Y4U9 | A0A0N4XS82 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uncharacterized protein. | 0.825 |
NBR_LOCUS11147 | NBR_LOCUS10956 | A0A0N4Y598 | A0A0N4Y4U9 | Malate synthase; Belongs to the malate synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.408 |
NBR_LOCUS11147 | NBR_LOCUS20942 | A0A0N4Y598 | A0A0N4YUM0 | Malate synthase; Belongs to the malate synthase family. | ADH_zinc_N domain-containing protein. | 0.664 |
NBR_LOCUS11147 | NBR_LOCUS4445 | A0A0N4Y598 | A0A0N4XPJ0 | Malate synthase; Belongs to the malate synthase family. | Aldo_ket_red domain-containing protein. | 0.864 |
NBR_LOCUS11147 | NBR_LOCUS7257 | A0A0N4Y598 | A0A0N4XWI4 | Malate synthase; Belongs to the malate synthase family. | Sorbitol dehydrogenase (inferred by orthology to a human protein). | 0.865 |
NBR_LOCUS13817 | NBR_LOCUS4445 | A0A0N4YBH8 | A0A0N4XPJ0 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (inferred by orthology to a human protein). | Aldo_ket_red domain-containing protein. | 0.697 |
NBR_LOCUS15378 | NBR_LOCUS10956 | A0A0N4YF60 | A0A0N4Y4U9 | Glutamate--cysteine ligase (inferred by orthology to a C. elegans protein). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.420 |
NBR_LOCUS15378 | NBR_LOCUS4445 | A0A0N4YF60 | A0A0N4XPJ0 | Glutamate--cysteine ligase (inferred by orthology to a C. elegans protein). | Aldo_ket_red domain-containing protein. | 0.791 |
NBR_LOCUS16536 | NBR_LOCUS10956 | A0A0N4YI20 | A0A0N4Y4U9 | Uncharacterized protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.825 |
NBR_LOCUS16536 | NBR_LOCUS4445 | A0A0N4YI20 | A0A0N4XPJ0 | Uncharacterized protein. | Aldo_ket_red domain-containing protein. | 0.706 |
NBR_LOCUS20942 | NBR_LOCUS10956 | A0A0N4YUM0 | A0A0N4Y4U9 | ADH_zinc_N domain-containing protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.463 |
NBR_LOCUS20942 | NBR_LOCUS11147 | A0A0N4YUM0 | A0A0N4Y598 | ADH_zinc_N domain-containing protein. | Malate synthase; Belongs to the malate synthase family. | 0.664 |
NBR_LOCUS20942 | NBR_LOCUS4445 | A0A0N4YUM0 | A0A0N4XPJ0 | ADH_zinc_N domain-containing protein. | Aldo_ket_red domain-containing protein. | 0.738 |
NBR_LOCUS20942 | NBR_LOCUS7257 | A0A0N4YUM0 | A0A0N4XWI4 | ADH_zinc_N domain-containing protein. | Sorbitol dehydrogenase (inferred by orthology to a human protein). | 0.921 |