STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS57782-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (131 aa)    
Predicted Functional Partners:
NBR_LOCUS20222
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
  
 
 0.954
NBR_LOCUS5776
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.
 
     0.915
NBR_LOCUS7257
Sorbitol dehydrogenase (inferred by orthology to a human protein).
  
 
  0.901
NBR_LOCUS12112
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (inferred by orthology to a human protein).
    
  0.837
NBR_LOCUS1815
Malonyl-CoA decarboxylase, mitochondrial (inferred by orthology to a human protein).
    
 0.831
NBR_LOCUS20166
Cholesterol desaturase daf-36 (inferred by orthology to a C. elegans protein).
    
  0.831
NBR_LOCUS2097
Aldo_ket_red domain-containing protein.
  
 
  0.788
NBR_LOCUS18372
Aldo_ket_red domain-containing protein.
  
 
  0.788
NBR_LOCUS14116
2Fe-2S ferredoxin-type domain-containing protein.
    
 0.777
NBR_LOCUS18078
Adrenodoxin, mitochondrial (inferred by orthology to a human protein).
    
 0.777
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.