STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS6120Estradiol 17-beta-dehydrogenase 12 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)    
Predicted Functional Partners:
NBR_LOCUS12211
Probable very-long-chain enoyl-CoA reductase art-1 (inferred by orthology to a C. elegans protein).
   
 0.993
NBR_LOCUS6414
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
 0.971
NBR_LOCUS22504
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
 0.955
NBR_LOCUS10570
Uncharacterized protein.
   
 0.946
NBR_LOCUS10571
Uncharacterized protein.
   
 0.946
NBR_LOCUS6792
Uncharacterized protein.
  
 0.930
NBR_LOCUS9680
3Beta_HSD domain-containing protein.
  
 0.929
NBR_LOCUS6787
Estradiol 17-beta-dehydrogenase 8 (inferred by orthology to a human protein).
 
 
 0.914
NBR_LOCUS10643
Probable cytochrome P450 CYP44 (inferred by orthology to a C. elegans protein); Belongs to the cytochrome P450 family.
  
 0.910
NBR_LOCUS16727
Uncharacterized protein.
  
 0.910
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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