STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS6901Helicase ATP-binding domain-containing protein. (931 aa)    
Predicted Functional Partners:
NBR_LOCUS1527
General transcription factor IIH subunit 3 (inferred by orthology to a human protein).
    
 0.998
NBR_LOCUS10763
Cyclin-H (inferred by orthology to a human protein).
    
 0.998
NBR_LOCUS12745
General transcription factor IIH subunit.
    
 0.998
NBR_LOCUS13911
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.998
NBR_LOCUS16341
Uncharacterized protein.
    
 0.998
NBR_LOCUS10286
Transcription initiation factor IIB (inferred by orthology to a C. elegans protein).
    
 0.997
NBR_LOCUS6607
DNA-directed RNA polymerase II subunit RPB3 (inferred by orthology to a human protein).
    
 0.996
NBR_LOCUS7407
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.996
NBR_LOCUS9791
Uncharacterized protein.
    
 0.996
NBR_LOCUS11155
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.996
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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