NBR_LOCUS8384 protein (Nippostrongylus brasiliensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NBR_LOCUS8384

Uncharacterized protein. (85 aa)

Predicted Functional Partners:

MED18

0.503

NBR_LOCUS14674

0.487

NBR_LOCUS8605

0.467

NBR_LOCUS6918

0.465

NBR_LOCUS4595

0.450

NBR_LOCUS21276

0.450

NBR_LOCUS18683

0.450

NBR_LOCUS1419

0.450

Your Current Organism:

Nippostrongylus brasiliensis

NCBI taxonomy Id: 27835
Other names: N. brasiliensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED18	NBR_LOCUS1419	A0A0N4XEQ9	A0A3P7AGC5	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.450
MED18	NBR_LOCUS14674	A0A0N4XEQ9	A0A158R1Y4	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	0.487
MED18	NBR_LOCUS18683	A0A0N4XEQ9	A0A158R3N6	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.518
MED18	NBR_LOCUS21276	A0A0N4XEQ9	A0A0N4YVK3	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.518
MED18	NBR_LOCUS4595	A0A0N4XEQ9	A0A0N4XPZ2	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	DNA-directed RNA polymerase III subunit RPC3 (inferred by orthology to a human protein).	0.450
MED18	NBR_LOCUS6918	A0A0N4XEQ9	A0A158QXI9	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	DUF3677 domain-containing protein.	0.482
MED18	NBR_LOCUS8384	A0A0N4XEQ9	A0A0N4XZ20	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.503
MED18	NBR_LOCUS8605	A0A0N4XEQ9	A0A0N4XZJ0	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.465
NBR_LOCUS1419	MED18	A0A3P7AGC5	A0A0N4XEQ9	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.450
NBR_LOCUS1419	NBR_LOCUS14674	A0A3P7AGC5	A0A158R1Y4	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	0.469
NBR_LOCUS1419	NBR_LOCUS18683	A0A3P7AGC5	A0A158R3N6	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.540
NBR_LOCUS1419	NBR_LOCUS21276	A0A3P7AGC5	A0A0N4YVK3	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.540
NBR_LOCUS1419	NBR_LOCUS8384	A0A3P7AGC5	A0A0N4XZ20	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.450
NBR_LOCUS1419	NBR_LOCUS8605	A0A3P7AGC5	A0A0N4XZJ0	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.693
NBR_LOCUS14674	MED18	A0A158R1Y4	A0A0N4XEQ9	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.487
NBR_LOCUS14674	NBR_LOCUS1419	A0A158R1Y4	A0A3P7AGC5	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.469
NBR_LOCUS14674	NBR_LOCUS18683	A0A158R1Y4	A0A158R3N6	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	Uncharacterized protein.	0.450
NBR_LOCUS14674	NBR_LOCUS21276	A0A158R1Y4	A0A0N4YVK3	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	Uncharacterized protein.	0.450
NBR_LOCUS14674	NBR_LOCUS4595	A0A158R1Y4	A0A0N4XPZ2	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	DNA-directed RNA polymerase III subunit RPC3 (inferred by orthology to a human protein).	0.469
NBR_LOCUS14674	NBR_LOCUS6918	A0A158R1Y4	A0A158QXI9	Phenylalanine--tRNA ligase alpha subunit (inferred by orthology to a human protein).	DUF3677 domain-containing protein.	0.408