STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS10349Uncharacterized protein. (121 aa)    
Predicted Functional Partners:
NBR_LOCUS11243
Polycomb protein mes-6 (inferred by orthology to a C. elegans protein).
    
 0.704
NBR_LOCUS13489
Set1/Ash2 histone methyltransferase complex subunit ASH2 (inferred by orthology to a human protein).
    
 0.666
NBR_LOCUS13840
Retinoblastoma-binding protein 5 (inferred by orthology to a human protein).
    
 0.666
NBR_LOCUS12461
Histone demethylase UTY (inferred by orthology to a human protein).
    
 0.664
NBR_LOCUS16038
TPR_REGION domain-containing protein.
    
 0.664
NBR_LOCUS338
Ubiquitin-60S ribosomal protein L40 (inferred by orthology to a C. elegans protein).
    
  0.652
NBR_LOCUS12625
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.650
NBR_LOCUS15847
Histone H4 (inferred by orthology to a zebrafish protein); Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.650
NBR_LOCUS17097
Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein).
    
 0.645
NBR_LOCUS18797
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.641
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.