STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS10660Coronin-like protein cor-1 (inferred by orthology to a C. elegans protein). (70 aa)    
Predicted Functional Partners:
NBR_LOCUS9367
GTP cyclohydrolase 1 (inferred by orthology to a C. elegans protein).
    
 0.862
NBR_LOCUS10552
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
    
 0.860
NBR_LOCUS5831
Molybdenum cofactor biosynthesis protein 1 (inferred by orthology to a D. melanogaster protein).
    
 0.859
NBR_LOCUS13724
Probable ubiquitin conjugation factor E4 (inferred by orthology to a C. elegans protein).
     
 0.831
NBR_LOCUS12258
Actin-depolymerizing factor 1 (inferred by orthology to a C. elegans protein); Belongs to the actin-binding proteins ADF family.
   
 0.808
NBR_LOCUS11817
Germline survival defective-1 (inferred by orthology to a C. elegans protein).
    
 0.802
NBR_LOCUS11818
Putative dihydrofolate reductase (inferred by orthology to a C. elegans protein); Belongs to the dihydrofolate reductase family.
    
 0.802
NBR_LOCUS15925
Putative folylpolyglutamate synthase (inferred by orthology to a C. elegans protein).
    
 0.768
NBR_LOCUS18810
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.768
NBR_LOCUS15285
Acyl-CoA dehydrogenase family member 10 (inferred by orthology to a human protein).
    
 0.764
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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