STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS10791Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (358 aa)    
Predicted Functional Partners:
NBR_LOCUS6587
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.999
NBR_LOCUS17552
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.999
NBR_LOCUS18036
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.999
NBR_LOCUS17803
Iso_dh domain-containing protein.
  
0.998
NBR_LOCUS12486
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.986
NBR_LOCUS12757
Citrate synthase; Belongs to the citrate synthase family.
  
 0.986
NBR_LOCUS16880
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.986
NBR_LOCUS7222
Pyruvate carboxyltransferase domain-containing protein.
  
 0.981
NBR_LOCUS11475
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.979
NBR_LOCUS17394
2-oxoglutarate dehydrogenase, mitochondrial (inferred by orthology to a C. elegans protein).
  
 0.979
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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