NBR_LOCUS12278 protein (Nippostrongylus brasiliensis)

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NBR_LOCUS12278

Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family. (386 aa)

Predicted Functional Partners:

NBR_LOCUS6406

0.991

NBR_LOCUS17617

0.977

NBR_LOCUS16194

0.971

NBR_LOCUS7622

0.966

NBR_LOCUS9408

0.953

NBR_LOCUS1197

0.936

NBR_LOCUS22745

0.936

NBR_LOCUS14570

0.936

NBR_LOCUS1097

0.930

NBR_LOCUS3121

0.930

Your Current Organism:

Nippostrongylus brasiliensis

NCBI taxonomy Id: 27835
Other names: N. brasiliensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NBR_LOCUS1097	NBR_LOCUS12278	A0A0N4XEZ4	A0A0N4Y7W7	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	0.930
NBR_LOCUS1097	NBR_LOCUS17617	A0A0N4XEZ4	A0A0N4YKN4	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	S-adenosylmethionine decarboxylase proenzyme.	0.490
NBR_LOCUS1097	NBR_LOCUS6406	A0A0N4XEZ4	A0A158QX84	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Alpha-aminoadipic semialdehyde synthase, mitochondrial (inferred by orthology to a human protein).	0.776
NBR_LOCUS1097	NBR_LOCUS9408	A0A0N4XEZ4	A0A0N4Y1C2	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.548
NBR_LOCUS1197	NBR_LOCUS12278	A0A0N4XF94	A0A0N4Y7W7	Orn_Arg_deC_N domain-containing protein.	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	0.936
NBR_LOCUS1197	NBR_LOCUS16194	A0A0N4XF94	A0A0N4YH74	Orn_Arg_deC_N domain-containing protein.	Uncharacterized protein.	0.915
NBR_LOCUS1197	NBR_LOCUS17617	A0A0N4XF94	A0A0N4YKN4	Orn_Arg_deC_N domain-containing protein.	S-adenosylmethionine decarboxylase proenzyme.	0.619
NBR_LOCUS1197	NBR_LOCUS6406	A0A0N4XF94	A0A158QX84	Orn_Arg_deC_N domain-containing protein.	Alpha-aminoadipic semialdehyde synthase, mitochondrial (inferred by orthology to a human protein).	0.907
NBR_LOCUS1197	NBR_LOCUS7622	A0A0N4XF94	A0A0N4XXC3	Orn_Arg_deC_N domain-containing protein.	Uncharacterized protein; Belongs to the arginase family.	0.912
NBR_LOCUS1197	NBR_LOCUS9408	A0A0N4XF94	A0A0N4Y1C2	Orn_Arg_deC_N domain-containing protein.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.753
NBR_LOCUS12278	NBR_LOCUS1097	A0A0N4Y7W7	A0A0N4XEZ4	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.930
NBR_LOCUS12278	NBR_LOCUS1197	A0A0N4Y7W7	A0A0N4XF94	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Orn_Arg_deC_N domain-containing protein.	0.936
NBR_LOCUS12278	NBR_LOCUS14570	A0A0N4Y7W7	A0A158R1W5	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Ornithine decarboxylase (inferred by orthology to a C. elegans protein); Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.936
NBR_LOCUS12278	NBR_LOCUS16194	A0A0N4Y7W7	A0A0N4YH74	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Uncharacterized protein.	0.971
NBR_LOCUS12278	NBR_LOCUS17617	A0A0N4Y7W7	A0A0N4YKN4	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	S-adenosylmethionine decarboxylase proenzyme.	0.977
NBR_LOCUS12278	NBR_LOCUS22745	A0A0N4Y7W7	A0A0N4YZS2	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Orn_Arg_deC_N domain-containing protein.	0.936
NBR_LOCUS12278	NBR_LOCUS3121	A0A0N4Y7W7	A0A0N4XKR8	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.930
NBR_LOCUS12278	NBR_LOCUS6406	A0A0N4Y7W7	A0A158QX84	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Alpha-aminoadipic semialdehyde synthase, mitochondrial (inferred by orthology to a human protein).	0.991
NBR_LOCUS12278	NBR_LOCUS7622	A0A0N4Y7W7	A0A0N4XXC3	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	Uncharacterized protein; Belongs to the arginase family.	0.966
NBR_LOCUS12278	NBR_LOCUS9408	A0A0N4Y7W7	A0A0N4Y1C2	Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.953