STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS12826Uncharacterized protein. (551 aa)    
Predicted Functional Partners:
NBR_LOCUS3694
Uncharacterized protein.
    
 0.868
NBR_LOCUS6120
Estradiol 17-beta-dehydrogenase 12 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.847
NBR_LOCUS9029
Uncharacterized protein.
 
      0.841
NBR_LOCUS9839
Elongation of very long chain fatty acids protein.
   
 0.833
NBR_LOCUS20782
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
   
 0.811
NBR_LOCUS12211
Probable very-long-chain enoyl-CoA reductase art-1 (inferred by orthology to a C. elegans protein).
     
 0.792
NBR_LOCUS6414
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
     
 0.770
NBR_LOCUS17624
Uncharacterized protein.
    
 0.770
NBR_LOCUS7980
Proteasome endopeptidase complex.
  
 0.764
NBR_LOCUS5637
Delta(5) fatty acid desaturase fat-4 (inferred by orthology to a C. elegans protein).
  
 0.764
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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