STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS13278PDE4_UCR domain-containing protein. (183 aa)    
Predicted Functional Partners:
NBR_LOCUS7566
Protein phosphatase PHLPP-like protein (inferred by orthology to a C. elegans protein).
    
 0.923
NBR_LOCUS10126
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.867
NBR_LOCUS18588
Adenosine kinase (inferred by orthology to a human protein).
     
 0.867
NBR_LOCUS12311
Phosphodiesterase.
 
  
 0.858
NBR_LOCUS14920
Phosphodiesterase delta-like protein (inferred by orthology to a C. elegans protein).
    
 0.856
NBR_LOCUS7798
Probable 3',5'-cyclic phosphodiesterase pde-4 (inferred by orthology to a C. elegans protein); Belongs to the cyclic nucleotide phosphodiesterase family.
 
      0.852
NBR_LOCUS5745
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.837
NBR_LOCUS7995
Probable 3',5'-cyclic phosphodiesterase pde-6 (inferred by orthology to a C. elegans protein); Belongs to the cyclic nucleotide phosphodiesterase family.
    
 0.829
NBR_LOCUS12814
Adenine phosphoribosyltransferase (inferred by orthology to a C. elegans protein).
     
 0.808
NBR_LOCUS1759
Protein kinase domain-containing protein.
   
 0.793
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.