STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS14612Uncharacterized protein. (823 aa)    
Predicted Functional Partners:
NBR_LOCUS1415
DIRP domain-containing protein.
    
 0.618
NBR_LOCUS21201
dUTPase domain-containing protein.
    
 0.605
NBR_LOCUS10052
Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein).
    
  0.504
NBR_LOCUS1984
Uncharacterized protein.
    
 0.491
NBR_LOCUS10371
Uncharacterized protein.
    
 0.491
NBR_LOCUS9
Probable histone-binding protein lin-53 (inferred by orthology to a C. elegans protein).
    
 0.473
NBR_LOCUS6816
Probable histone-binding protein Caf1 (inferred by orthology to a D. melanogaster protein).
    
 0.473
NBR_LOCUS22194
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.460
NBR_LOCUS12142
DNA repair endonuclease XPF (inferred by orthology to a D. melanogaster protein).
    
  0.451
NBR_LOCUS12145
DNA repair endonuclease XPF (inferred by orthology to a D. melanogaster protein).
    
  0.451
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.