STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS15375Uncharacterized protein. (377 aa)    
Predicted Functional Partners:
NBR_LOCUS16488
PHD domain-containing protein.
    
 0.832
NBR_LOCUS14352
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.826
NBR_LOCUS10874
26S proteasome non-ATPase regulatory subunit 3 (inferred by orthology to a C. elegans protein).
    
 0.799
NBR_LOCUS12625
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.775
NBR_LOCUS15847
Histone H4 (inferred by orthology to a zebrafish protein); Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.775
NBR_LOCUS9623
Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
    
 0.742
NBR_LOCUS13489
Set1/Ash2 histone methyltransferase complex subunit ASH2 (inferred by orthology to a human protein).
    
 0.736
NBR_LOCUS16085
Sex muscle abnormal protein 5 (inferred by orthology to a C. elegans protein).
   
  0.733
NBR_LOCUS13840
Retinoblastoma-binding protein 5 (inferred by orthology to a human protein).
    
 0.724
NBR_LOCUS4666
Uncharacterized protein.
   
 0.723
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.