STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS17558N-acetyltransferase domain-containing protein. (263 aa)    
Predicted Functional Partners:
NBR_LOCUS16819
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.879
NBR_LOCUS11283
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.
   
 0.832
NBR_LOCUS1090
Probable helicase senataxin (inferred by orthology to a human protein).
    
 0.804
NBR_LOCUS6212
AAA_12 domain-containing protein.
    
 0.804
NBR_LOCUS11111
Regulator of nonsense transcripts 1 (inferred by orthology to a C. elegans protein).
    
 0.804
NBR_LOCUS16982
Probable helicase senataxin (inferred by orthology to a human protein).
    
 0.804
NBR_LOCUS16025
Uncharacterized protein.
    
 0.804
NBR_LOCUS7674
Uncharacterized protein.
    
 0.771
NBR_LOCUS18
Protein mago nashi homolog (inferred by orthology to a C. elegans protein).
    
 0.712
NBR_LOCUS17382
Nuclear cap-binding protein subunit 1 (inferred by orthology to a C. elegans protein).
     
 0.704
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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