STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS18130Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (632 aa)    
Predicted Functional Partners:
NBR_LOCUS1039
Uncharacterized protein.
   
 0.992
NBR_LOCUS4438
Uncharacterized protein.
   
 0.988
NBR_LOCUS2764
Pre-mRNA 3' end processing protein WDR33 (inferred by orthology to a human protein).
   
 0.978
NBR_LOCUS16865
Uncharacterized protein.
   
 0.978
NBR_LOCUS20375
Pre-mRNA 3' end processing protein WDR33 (inferred by orthology to a human protein).
   
 0.978
NBR_LOCUS14736
Serine/threonine-protein kinase RIO1 (inferred by orthology to a human protein).
    
 
 0.968
NBR_LOCUS5967
Serine/threonine kinase SAD-1 (inferred by orthology to a C. elegans protein).
    
 0.944
NBR_LOCUS12625
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.922
NBR_LOCUS15847
Histone H4 (inferred by orthology to a zebrafish protein); Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.918
NBR_LOCUS10739
Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
    
 
 0.913
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.