STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS19309E3 ubiquitin-protein ligase CHIP (inferred by orthology to a human protein). (110 aa)    
Predicted Functional Partners:
NBR_LOCUS5980
Ubiquitin-conjugating enzyme E2 N (inferred by orthology to a D. melanogaster protein); Belongs to the ubiquitin-conjugating enzyme family.
   
 0.980
NBR_LOCUS21452
Ubiquitin-conjugating enzyme E2 2 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.
   
 0.976
NBR_LOCUS21179
Heat shock protein 90 (inferred by orthology to a C. elegans protein).
    
 0.968
NBR_LOCUS4060
Ubiquitin-conjugating enzyme E2-17 kDa (inferred by orthology to a D. melanogaster protein).
   
 0.843
NBR_LOCUS11861
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.796
NBR_LOCUS18797
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.785
NBR_LOCUS1001
Heat shock protein 75 kDa, mitochondrial (inferred by orthology to a human protein).
    
 0.776
NBR_LOCUS8279
Hamartin (inferred by orthology to a human protein).
    
 0.776
NBR_LOCUS11905
Heat shock protein 75 kDa, mitochondrial (inferred by orthology to a human protein).
    
 0.776
NBR_LOCUS17668
Runt domain-containing protein.
    
 0.765
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.