STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS19488Decapping and exoribonuclease protein (inferred by orthology to a human protein). (273 aa)    
Predicted Functional Partners:
NBR_LOCUS7121
5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle.
   
 
 0.959
NBR_LOCUS5678
Uncharacterized protein.
    
 
 0.956
NBR_LOCUS13476
Exosome complex component RRP42 (inferred by orthology to a human protein).
   
   0.931
NBR_LOCUS15777
CID domain-containing protein.
    
 
 0.745
NBR_LOCUS315
5'-3' exoribonuclease 1 (inferred by orthology to a human protein).
    
 
 0.543
NBR_LOCUS22051
Exosome component 10 (inferred by orthology to a human protein).
   
 
 0.507
NBR_LOCUS3117
MKI67 FHA domain-interacting nucleolar phosphoprotein (inferred by orthology to a human protein).
   
 
 0.445
NBR_LOCUS13334
Putative exosome complex component RRP41 (inferred by orthology to a C. elegans protein).
   
 
 0.443
NBR_LOCUS16065
RTR1-type domain-containing protein.
   
   0.422
NBR_LOCUS10332
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
   0.416
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.