STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS19660H15 domain-containing protein. (200 aa)    
Predicted Functional Partners:
NBR_LOCUS1984
Uncharacterized protein.
    
 0.938
NBR_LOCUS10371
Uncharacterized protein.
    
 0.938
NBR_LOCUS12625
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.928
NBR_LOCUS15847
Histone H4 (inferred by orthology to a zebrafish protein); Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.905
NBR_LOCUS8185
Importin subunit beta-1 (inferred by orthology to a human protein).
    
   0.840
NBR_LOCUS8186
Importin subunit beta-1 (inferred by orthology to a human protein).
    
   0.840
NBR_LOCUS18328
Histone H2A; Belongs to the histone H2A family.
   
 0.767
NBR_LOCUS21361
Calreticulin.
    
  0.767
NBR_LOCUS9111
High mobility group protein 1.2 (inferred by orthology to a C. elegans protein).
    
 0.728
NBR_LOCUS1302
Putative centromere protein A (inferred by orthology to a S. mansoni protein).
   
 
 0.671
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.