STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS20454Uncharacterized protein. (112 aa)    
Predicted Functional Partners:
NBR_LOCUS8175
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.908
NBR_LOCUS696
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.739
NBR_LOCUS10940
Protein-serine/threonine kinase.
     
 0.683
NBR_LOCUS2862
Uncharacterized protein.
    
 0.663
NBR_LOCUS7009
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.663
NBR_LOCUS7010
Inositol polyphosphate multikinase (inferred by orthology to a human protein).
    
 0.663
NBR_LOCUS15010
Putative H/ACA ribonucleoprotein complex subunit 4 (inferred by orthology to a C. elegans protein).
    
 
 0.430
NBR_LOCUS45
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
   0.424
NBR_LOCUS18789
Probable tRNA pseudouridine synthase 2 (inferred by orthology to a human protein).
    
 
 0.403
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.