STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS21445Chromo domain-containing protein. (176 aa)    
Predicted Functional Partners:
NBR_LOCUS15966
Poly(ADP-ribose) glycohydrolase (inferred by orthology to a human protein).
    
 0.834
NBR_LOCUS12375
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.789
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.774
NBR_LOCUS12446
DNA repair protein complementing XP-C cells (inferred by orthology to a human protein).
    
 0.742
NBR_LOCUS18357
Uncharacterized calcium-binding protein (inferred by orthology to a C. elegans protein).
    
 0.741
NBR_LOCUS1984
Uncharacterized protein.
    
 0.714
NBR_LOCUS10371
Uncharacterized protein.
    
 0.714
NBR_LOCUS4120
Uncharacterized protein.
   
 0.705
NBR_LOCUS17097
Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein).
    
  0.681
NBR_LOCUS7778
Uncharacterized protein.
    
 0.665
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (16%) [HD]