node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | NBR_LOCUS10371 | A0A0N4Y9Y7 | A0A158QZM8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.890 |
FEN1 | NBR_LOCUS12446 | A0A0N4Y9Y7 | A0A158R0S6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein complementing XP-C cells (inferred by orthology to a human protein). | 0.813 |
FEN1 | NBR_LOCUS15966 | A0A0N4Y9Y7 | A0A158R2I0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly(ADP-ribose) glycohydrolase (inferred by orthology to a human protein). | 0.803 |
FEN1 | NBR_LOCUS17097 | A0A0N4Y9Y7 | A0A0N4YJF8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.559 |
FEN1 | NBR_LOCUS1984 | A0A0N4Y9Y7 | A0A0N4XHI1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.890 |
FEN1 | NBR_LOCUS21445 | A0A0N4Y9Y7 | A0A0N4YW22 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Chromo domain-containing protein. | 0.774 |
FEN1 | NBR_LOCUS4120 | A0A0N4Y9Y7 | A0A0N4XNL8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.978 |
FEN1 | NBR_LOCUS7778 | A0A0N4Y9Y7 | A0A0N4XXP1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.735 |
NBR_LOCUS10371 | FEN1 | A0A158QZM8 | A0A0N4Y9Y7 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.890 |
NBR_LOCUS10371 | NBR_LOCUS12446 | A0A158QZM8 | A0A158R0S6 | Uncharacterized protein. | DNA repair protein complementing XP-C cells (inferred by orthology to a human protein). | 0.868 |
NBR_LOCUS10371 | NBR_LOCUS17097 | A0A158QZM8 | A0A0N4YJF8 | Uncharacterized protein. | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.738 |
NBR_LOCUS10371 | NBR_LOCUS18357 | A0A158QZM8 | A0A0N4YMG2 | Uncharacterized protein. | Uncharacterized calcium-binding protein (inferred by orthology to a C. elegans protein). | 0.840 |
NBR_LOCUS10371 | NBR_LOCUS21445 | A0A158QZM8 | A0A0N4YW22 | Uncharacterized protein. | Chromo domain-containing protein. | 0.714 |
NBR_LOCUS10371 | NBR_LOCUS4120 | A0A158QZM8 | A0A0N4XNL8 | Uncharacterized protein. | Uncharacterized protein. | 0.848 |
NBR_LOCUS10371 | NBR_LOCUS7778 | A0A158QZM8 | A0A0N4XXP1 | Uncharacterized protein. | Uncharacterized protein. | 0.600 |
NBR_LOCUS12375 | NBR_LOCUS17097 | A0A0N4Y850 | A0A0N4YJF8 | Uncharacterized protein; Belongs to the peptidase C14A family. | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.779 |
NBR_LOCUS12375 | NBR_LOCUS21445 | A0A0N4Y850 | A0A0N4YW22 | Uncharacterized protein; Belongs to the peptidase C14A family. | Chromo domain-containing protein. | 0.789 |
NBR_LOCUS12446 | FEN1 | A0A158R0S6 | A0A0N4Y9Y7 | DNA repair protein complementing XP-C cells (inferred by orthology to a human protein). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.813 |
NBR_LOCUS12446 | NBR_LOCUS10371 | A0A158R0S6 | A0A158QZM8 | DNA repair protein complementing XP-C cells (inferred by orthology to a human protein). | Uncharacterized protein. | 0.868 |
NBR_LOCUS12446 | NBR_LOCUS17097 | A0A158R0S6 | A0A0N4YJF8 | DNA repair protein complementing XP-C cells (inferred by orthology to a human protein). | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.978 |