node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NBR_LOCUS10052 | NBR_LOCUS10991 | A0A0N4Y2T3 | A0A0N4Y4X6 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.993 |
NBR_LOCUS10052 | NBR_LOCUS11316 | A0A0N4Y2T3 | A0A158R077 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.810 |
NBR_LOCUS10052 | NBR_LOCUS11994 | A0A0N4Y2T3 | A0A158R0K5 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.930 |
NBR_LOCUS10052 | NBR_LOCUS11996 | A0A0N4Y2T3 | A0A0N4Y777 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.930 |
NBR_LOCUS10052 | NBR_LOCUS17097 | A0A0N4Y2T3 | A0A0N4YJF8 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.995 |
NBR_LOCUS10052 | NBR_LOCUS18797 | A0A0N4Y2T3 | A0A0N4YNI4 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.996 |
NBR_LOCUS10052 | NBR_LOCUS21600 | A0A0N4Y2T3 | A0A0N4YWH7 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | Uncharacterized protein. | 0.850 |
NBR_LOCUS10052 | NBR_LOCUS22194 | A0A0N4Y2T3 | A0A0N4YY69 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.682 |
NBR_LOCUS10052 | NBR_LOCUS9214 | A0A0N4Y2T3 | A0A0N4Y0W4 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | RecQ-mediated genome instability protein 1 (inferred by orthology to a human protein). | 0.955 |
NBR_LOCUS10052 | NBR_LOCUS9433 | A0A0N4Y2T3 | A0A158QZ27 | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | DNA excision repair protein ERCC-1 (inferred by orthology to a human protein). | 0.993 |
NBR_LOCUS10991 | NBR_LOCUS10052 | A0A0N4Y4X6 | A0A0N4Y2T3 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | 0.993 |
NBR_LOCUS10991 | NBR_LOCUS17097 | A0A0N4Y4X6 | A0A0N4YJF8 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.999 |
NBR_LOCUS10991 | NBR_LOCUS18797 | A0A0N4Y4X6 | A0A0N4YNI4 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.999 |
NBR_LOCUS10991 | NBR_LOCUS21600 | A0A0N4Y4X6 | A0A0N4YWH7 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Uncharacterized protein. | 0.853 |
NBR_LOCUS10991 | NBR_LOCUS22194 | A0A0N4Y4X6 | A0A0N4YY69 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.671 |
NBR_LOCUS10991 | NBR_LOCUS9433 | A0A0N4Y4X6 | A0A158QZ27 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | DNA excision repair protein ERCC-1 (inferred by orthology to a human protein). | 0.915 |
NBR_LOCUS11316 | NBR_LOCUS10052 | A0A158R077 | A0A0N4Y2T3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Nuclear protein localization protein 4 homolog (inferred by orthology to a human protein). | 0.810 |
NBR_LOCUS11316 | NBR_LOCUS11994 | A0A158R077 | A0A158R0K5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.828 |
NBR_LOCUS11316 | NBR_LOCUS11996 | A0A158R077 | A0A0N4Y777 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.828 |
NBR_LOCUS11316 | NBR_LOCUS17097 | A0A158R077 | A0A0N4YJF8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein). | 0.446 |