STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS21863E3 ubiquitin-protein ligase ARIH1 (inferred by orthology to a human protein). (147 aa)    
Predicted Functional Partners:
NBR_LOCUS17884
Ubiquitin/ISG15-conjugating enzyme E2 L6 (inferred by orthology to a human protein).
   
 0.983
NBR_LOCUS3423
RING-box protein 1 (inferred by orthology to a C. elegans protein).
    
 0.978
NBR_LOCUS17097
Ubiquitin-40S ribosomal protein S27a (inferred by orthology to a human protein).
    
 0.976
NBR_LOCUS338
Ubiquitin-60S ribosomal protein L40 (inferred by orthology to a C. elegans protein).
    
  0.974
NBR_LOCUS5757
Cullin-6 (inferred by orthology to a C. elegans protein); Belongs to the cullin family.
   
 0.970
NBR_LOCUS8276
Cullin-3 (inferred by orthology to a C. elegans protein); Belongs to the cullin family.
   
 0.919
NBR_LOCUS18797
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.898
NBR_LOCUS5980
Ubiquitin-conjugating enzyme E2 N (inferred by orthology to a D. melanogaster protein); Belongs to the ubiquitin-conjugating enzyme family.
   
 0.808
NBR_LOCUS5656
Eukaryotic translation initiation factor 4E-4 (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic initiation factor 4E family.
    
 0.787
NBR_LOCUS15526
Uncharacterized protein.
    
 0.780
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.