STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS7326Acetolactate synthase-like protein (inferred by orthology to a C. elegans protein); Belongs to the TPP enzyme family. (625 aa)    
Predicted Functional Partners:
NBR_LOCUS11147
Malate synthase; Belongs to the malate synthase family.
  
 
 0.982
NBR_LOCUS7222
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.966
NBR_LOCUS13633
FMN hydroxy acid dehydrogenase domain-containing protein.
  
 
 0.932
NBR_LOCUS6819
Transket_pyr domain-containing protein.
  
 
 0.929
NBR_LOCUS13583
Fe-ADH domain-containing protein.
    
 0.925
NBR_LOCUS8072
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.924
NBR_LOCUS12757
Citrate synthase; Belongs to the citrate synthase family.
    
 0.922
NBR_LOCUS8589
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.910
NBR_LOCUS18695
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.909
NBR_LOCUS1911
Branched-chain-amino-acid aminotransferase (inferred by orthology to a D. melanogaster protein).
  
 0.907
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.