STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS8451Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (445 aa)    
Predicted Functional Partners:
NBR_LOCUS15190
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
 
 0.998
NBR_LOCUS11727
Kynurenine formamidase (inferred by orthology to a D. melanogaster protein).
  
 
 0.970
NBR_LOCUS6711
Kynurenine--oxoglutarate transaminase 1 (inferred by orthology to a human protein).
   
 
 0.968
NBR_LOCUS19277
Serine--pyruvate aminotransferase.
   
 
 0.924
NBR_LOCUS20077
Serine--pyruvate aminotransferase (inferred by orthology to a human protein).
   
 
 0.924
NBR_LOCUS17624
Uncharacterized protein.
   
 0.914
NBR_LOCUS11850
Uncharacterized protein.
   
 
 0.912
NBR_LOCUS20166
Cholesterol desaturase daf-36 (inferred by orthology to a C. elegans protein).
  
 
 0.912
NBR_LOCUS18139
Uncharacterized protein.
  
 
 0.901
NBR_LOCUS785
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
  
 0.891
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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