STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS9172Uncharacterized protein. (195 aa)    
Predicted Functional Partners:
NBR_LOCUS11200
Uncharacterized protein.
    
 
 0.650
NBR_LOCUS10382
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.578
NBR_LOCUS15814
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.578
NBR_LOCUS15520
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
   
    0.528
NBR_LOCUS9083
Uncharacterized protein.
   
    0.521
NBR_LOCUS14020
tRNA methyltransferase 10 homolog A (inferred by orthology to a human protein).
   
  
 0.521
NBR_LOCUS9917
Lethal (2) 09851 (inferred by orthology to a D. melanogaster protein).
   
    0.517
NBR_LOCUS10357
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.502
NBR_LOCUS8157
Presenilin hop-1 (inferred by orthology to a C. elegans protein).
    
 
 0.502
NBR_LOCUS12425
Uncharacterized protein.
   
  
 0.493
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.