STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBR_LOCUS3232Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (260 aa)    
Predicted Functional Partners:
NBR_LOCUS14429
Uncharacterized protein.
   
 0.974
NBR_LOCUS15371
WD_REPEATS_REGION domain-containing protein.
   
 0.974
NBR_LOCUS16392
Protein bicaudal D (inferred by orthology to a D. melanogaster protein).
    
 0.963
NBR_LOCUS12217
Dynactin subunit 1 (inferred by orthology to a human protein).
   
 0.947
NBR_LOCUS15413
CAP-Gly domain-containing protein.
   
 0.947
NBR_LOCUS11329
Dynein light chain Tctex-type 3 (inferred by orthology to a human protein).
    
 0.928
NBR_LOCUS7969
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.910
NBR_LOCUS16605
Dynactin subunit 6 (inferred by orthology to a C. elegans protein).
    
 0.896
NBR_LOCUS12611
Uncharacterized protein; Belongs to the actin family.
   
 0.887
NBR_LOCUS22291
Probable dynactin subunit 2 (inferred by orthology to a C. elegans protein).
   
 0.886
Your Current Organism:
Nippostrongylus brasiliensis
NCBI taxonomy Id: 27835
Other names: N. brasiliensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.