STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGM_202844Gamma-secretase subunit Aph-1 like protein. (240 aa)    
Predicted Functional Partners:
KGM_204430
Nicastrin.
   
 0.990
KGM_200464
Presenilin enhancer.
   
 0.988
KGM_202258
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.988
KGM_206801
Receptor protein-tyrosine kinase.
     
 0.597
KGM_200981
Mitochondrial carnitine/acylcarnitine translocase; Belongs to the mitochondrial carrier (TC 2.A.29) family.
 
    
 0.546
KGM_203934
Putative laminin A chain.
      
 0.525
KGM_214716
Transmembrane trafficking protein.
      
 0.480
KGM_212363
Putative myosin x; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.441
Your Current Organism:
Danaus plexippus
NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.